+ Reply to Thread
Results 1 to 3 of 3

Thread: Theoretical human proteome quantification profile!

  1. #1
    Angiotensin Member
    Join Date
    Nov 2011
    Location
    Tehran, Iran
    Posts
    42

    Theoretical human proteome quantification profile!

    Hi All

    I was wondering how can we make a theoretical human proteome quantify profile? Is it possible to do it? I mean there is a paper from Gygi SP (http://www.ncbi.nlm.nih.gov/pubmed?t...%202000%20PNAS) where they used Codon bias to evalute 2-DE. However, codon bias can not be used on human. There is emPAI (http://www.ncbi.nlm.nih.gov/pubmed?t...n%202005%20MCP) introduce by Mann. Here you need to have experiment data also. Is there software where we can give the human proteome database such as UniProtKB/Swiis-Prot and give us some index for abundancy of proteins? I am going to far ... I am not a programming guy, I am only interested in the programs which can do it ...

    Thanks
    Last edited by Kambiz; 04-24-2012 at 02:25 AM.

  2. #2
    Glycine Member
    Join Date
    Oct 2011
    Posts
    5
    Check out the GPM's human proteome guide. It's a report, not an algorithm, but it gives a great overview of observable proteins and the number of observations, which gives a rough guide to overall quantity.
    http://thegpm.org/lists/index.html#201008121

  3. #3
    Albumin Member
    Join Date
    Sep 2011
    Location
    Delhi
    Posts
    82
    I dont know about whole proteome but ISB people have something on Estimated Concentrations on proteins in Human Plasma.

+ Reply to Thread

Thread Information

Users Browsing this Thread

There are currently 1 users browsing this thread. (0 members and 1 guests)

     

Bookmarks

Posting Permissions

  • You may not post new threads
  • You may not post replies
  • You may not post attachments
  • You may not edit your posts

SharedProteomics
an online proteomics community